DLG5-AS1

Across TCGA pan-cancer cohorts, DLG5-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated DLG5-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher DLG5-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated DLG5-AS1 expression acts as an unfavorable survival marker, although some lineages such as BRCA and CESC show a favorable association.

KIRC, BRCA, and UVM are the cancer types where DLG5-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	II,III,IV	0.449	0.607	.003	75	view →
BRCA	DFS	Median	II,III,IV	0.555	0.470	<.001	74	view →
UVM	DFS	Median	III,IV	0.192	0.897	<.001	57	view →
CESC	OS	Quartile	III,IV	0.906	0.303	.002	38	view →
LGG	OS	Tertile	All	0.846	0.735	.003	29	view →
UCEC	DFS	Tertile	All	0.782	0.567	<.001	28	view →
BLCA	DFS	Tertile	IV	0.179	0.672	.004	19	view →
ACC	OS	Quartile	All	0.233	1.000	<.001	18	view →
THYM	OS	Quartile	All	0.596	0.922	.004	15	view →
SKCM	OS	Tertile	IV	0.173	0.818	.015	12	view →
KIRP	DFS	Quartile	All	0.859	0.983	.010	10	view →
OV	OS	Median	IV	0.738	0.513	.010	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

DLG5-AS1–KIRC (DFS)

Open the KIRC breakdown →