DLG5-AS1

Across TCGA pan-cancer cohorts, DLG5-AS1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of DLG5-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where DLG5-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types DLG5-AS1 is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.

LIHC, KIRC, and LUSC are the cancer types where DLG5-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DLG5-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	Male	II,III,IV	+1.986	<.001	9	view →
KIRC	All	II,III,IV	−0.414	<.001	6	view →
LUSC	Male	All	+0.727	<.001	5	view →
KICH	All	All	−0.513	.015	4	view →
LUAD	All	All	+0.378	.005	4	view →
COAD	All	All	+0.342	.006	4	view →
CHOL	All	All	+1.312	<.001	3	view →
HNSC	Male	III,IV	+0.595	.006	2	view →
PRAD	All	All	−0.357	<.001	2	view →
THCA	Male	IV	−1.200	.024	1	view →
ESCA	Male	All	+0.751	.034	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

DLG5-AS1–LIHC

Open the LIHC breakdown →