DLG3-AS1

Across TCGA pan-cancer cohorts, DLG3-AS1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated DLG3-AS1 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher DLG3-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated DLG3-AS1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and BLCA show a favorable association.

HNSC, BLCA, and UVM are the cancer types where DLG3-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Quartile	All	0.790	0.646	.001	70	view →
BLCA	OS	Tertile	All	0.681	0.522	.007	48	view →
UVM	DFS	Tertile	All	0.354	0.823	.002	45	view →
LGG	OS	Tertile	All	0.721	0.852	<.001	43	view →
BRCA	DFS	Tertile	IV	0.864	0.316	.001	35	view →
STAD	OS	Median	IV	0.563	0.180	.007	30	view →
OV	OS	Median	II,III,IV	0.888	0.793	.004	24	view →
KICH	OS	Quartile	All	0.678	1.000	.003	20	view →
KIRP	OS	Median	II,III,IV	0.913	0.735	.006	16	view →
SKCM	OS	Median	III,IV	0.502	0.292	.002	15	view →
THCA	DFS	Tertile	All	0.961	0.906	.008	12	view →
GBM	OS	Median	All	0.358	0.469	.035	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

DLG3-AS1–HNSC (DFS)

Open the HNSC breakdown →