DLG3-AS1

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, DLG3-AS1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of DLG3-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where DLG3-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types DLG3-AS1 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

LUAD, THCA, and BRCA are the cancer types where DLG3-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DLG3-AS1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
LUADFemaleAll+0.772<.00111view →
THCAMaleAll−0.817<.0019view →
BRCAAllAll+0.620<.0016view →
STADAllAll+0.428.0045view →
BLCAAllAll+0.393.0025view →
KIRPAllAll+0.506<.0014view →
CHOLAllAll+0.515<.0013view →
KICHAllIII,IV−0.352.0113view →
LUSCFemaleAll+1.077.0152view →
PRADAllAll+0.917<.0012view →
PAADMaleAll+0.420.0482view →
LIHCFemaleAll+0.089.0341view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

DLG3-AS1–LUAD

Tumor-vs-normal expression box plot for DLG3-AS1 RNA in LUAD.

Open the LUAD breakdown →

Exploration