DLG2-AS2

Across TCGA pan-cancer cohorts, DLG2-AS2 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated DLG2-AS2 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher DLG2-AS2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated DLG2-AS2 expression acts as an unfavorable survival marker, although some lineages such as UCS and LUAD show a favorable association.

KIRC, CESC, and DLBC are the cancer types where DLG2-AS2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Quartile	II,III,IV	0.401	0.585	.005	37	view →
CESC	OS	Tertile	IV	0.091	0.593	<.001	36	view →
DLBC	OS	Tertile	III,IV	0.272	1.000	.017	30	view →
UCS	OS	Tertile	All	0.692	0.263	.014	30	view →
SKCM	DFS	Tertile	III,IV	0.297	0.529	.005	27	view →
UCEC	OS	Tertile	All	0.812	0.886	.015	24	view →
LUAD	OS	Tertile	II,III,IV	0.817	0.672	.013	15	view →
GBM	DFS	Quartile	All	0.456	0.235	.023	12	view →
ESCA	OS	Quartile	II,III,IV	0.790	0.436	.010	10	view →
THCA	DFS	Median	All	0.961	0.910	.018	6	view →
TGCT	OS	Quartile	II,III,IV	0.670	1.000	.020	6	view →
LUSC	OS	Tertile	All	0.334	0.416	.037	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

DLG2-AS2–KIRC (DFS)

Open the KIRC breakdown →