DLG1

Across TCGA patient cohorts, DLG1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,215 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DLG1-associated genes across cancer lineages are LAG3, LILRB3, and DNAJC19. Each is linked with DLG1 in more than 7 cancer types. Because this analysis shows association rather than direction, both DLG1-to-partner and partner-to-DLG1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DLG1 versus LAG3 in UCEC, with a Pearson correlation of -0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DLG1→partner) and Y-score (partner→DLG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LAG3 →	-0.980	-0.282	<.001	<.001	3	8
COAD	LILRB3 →	-0.753	-0.191	<.001	<.001	3	7
LSCC	DNAJC19 →	+0.836	+0.381	<.001	<.001	3	7
OV	LILRB1 →	-0.731	-0.272	.002	.004	3	7
UCEC	NIPAL2 →	+0.696	+0.362	<.001	<.001	3	6
LSCC	TMEM254 →	+0.742	+0.504	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,215 associations by consensus.

DLG1 vs LAG3 — UCEC

Explore this scatter interactively →