DLEC1

Across TCGA patient cohorts, DLEC1 protein abundance is significantly associated with the RNA expression of many other genes, with 423 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DLEC1-associated genes across cancer lineages are HRH3, NALCN, and NHP2P1. Each is linked with DLEC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DLEC1-to-partner and partner-to-DLEC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DLEC1 versus HRH3 in GBM, with a Pearson correlation of 0.95.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DLEC1→partner) and Y-score (partner→DLEC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	HRH3 →	+0.626	+1.253	.003	.005	3	1
GBM	NALCN →	+1.420	+0.917	.004	.005	3	1
GBM	NHP2P1 →	+1.343	+1.253	.006	.005	3	1
GBM	WNT2 →	+1.779	+1.426	<.001	.004	3	1
GBM	AIMP2 →	-0.740	-1.253	<.001	.005	3	1
GBM	SH3GL2 →	+3.132	+0.916	.008	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 423 associations by consensus.

DLEC1 vs HRH3 — GBM

Explore this scatter interactively →