DLEC1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, DLEC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,604 significant associations in total. LIVER shows the largest number of these associations.

The most reproducible DLEC1-associated GO terms across cancer lineages are Cilium or flagellum-dependent cell motility, Cilium-dependent cell motility, and Flagellated sperm motility. Each is linked with DLEC1 in more than 12 cancer types. Because this analysis shows association rather than direction, both DLEC1-to-partner and partner-to-DLEC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cilium or flagellum-dependent cell motility grouped by DLEC1-low versus DLEC1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DLEC1→partner) and Y-score (partner→DLEC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UPPER_AERODIGESTIVE_TRACTCilium or flagellum-dependent cell motility →-0.112-0.214<.001.002313
UPPER_AERODIGESTIVE_TRACTCilium-dependent cell motility →-0.112-0.214<.001.002313
UPPER_AERODIGESTIVE_TRACTFlagellated sperm motility →-0.113-0.190<.001<.001312
UPPER_AERODIGESTIVE_TRACTCilium movement involved in cell motility →-0.106-0.167<.001.004312
UPPER_AERODIGESTIVE_TRACTSperm motility →-0.113-0.190<.001<.001312
LIVERFatty acid catabolic process →+0.067+0.109.006.008310
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,604 associations by consensus.

Cilium or flagellum-dependent cell motility by DLEC1 expression — UPPER_AERODIGESTIVE_TRACT

Box plot of Cilium or flagellum-dependent cell motility in DLEC1-low vs DLEC1-high samples in UPPER_AERODIGESTIVE_TRACT.

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Exploration