DKKL1

Across TCGA patient cohorts, DKKL1 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,459 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DKKL1-associated proteins across cancer lineages are UNC119B, UPF3B, and POGZ. Each is linked with DKKL1 in more than 2 cancer types. Because this analysis shows association rather than direction, both DKKL1-to-partner and partner-to-DKKL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DKKL1 versus UNC119B in LSCC, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DKKL1→partner) and Y-score (partner→DKKL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	UNC119B →	+0.233	+0.645	<.001	<.001	3	3
LSCC	UPF3B →	+0.226	+0.518	.008	.003	3	3
LSCC	POGZ →	+0.303	+0.584	.002	<.001	3	3
OV	MSI1 →	+0.680	+0.606	.009	.009	3	3
LSCC	MBD3 →	+0.412	+0.509	.003	.001	3	3
LSCC	MSH6 →	+0.572	+0.530	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,459 associations by consensus.

DKKL1 vs UNC119B — LSCC

Explore this scatter interactively →