DIPK2A

Across TCGA cell cohorts, DIPK2A mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible DIPK2A-associated genes across cancer lineages are GSG1L2, KRTAP9-1, and STRA8. Each is linked with DIPK2A in more than 1 cancer types. Because this analysis shows association rather than direction, both DIPK2A-to-partner and partner-to-DIPK2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GSG1L2 grouped by DIPK2A-low versus DIPK2A-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DIPK2A→partner) and Y-score (partner→DIPK2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GSG1L2 →	+0.016	+4.437	<.001	.004	3	1
BLOOD_Lymphoma	KRTAP9-1 →	+0.040	+5.247	<.001	.001	3	1
LUNG_NSCLC_LUAD	STRA8 →	+0.433	+3.544	<.001	.009	3	1
LUNG_NSCLC_LUAD	WFDC8 →	+0.012	+4.189	<.001	.002	3	1
LUNG_NSCLC_LUAD	OR2V2 →	+0.032	+3.544	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR13C8 →	+0.021	+4.078	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

GSG1L2 by DIPK2A expression — LARGE_INTESTINE

Explore this box plot interactively →