DIAPH2-AS1

Across TCGA pan-cancer cohorts, DIAPH2-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated DIAPH2-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher DIAPH2-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated DIAPH2-AS1 expression acts as an unfavorable survival marker, although some lineages such as SKCM and UCS show a favorable association.

KIRC, SKCM, and KIRP are the cancer types where DIAPH2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.544	0.702	<.001	125	view →
SKCM	OS	Median	All	0.417	0.258	<.001	118	view →
KIRP	DFS	Tertile	All	0.705	0.898	<.001	116	view →
HNSC	OS	Median	IV	0.346	0.679	.001	79	view →
UCEC	DFS	Median	All	0.543	0.737	<.001	50	view →
COAD	DFS	Median	III,IV	0.301	0.694	.002	31	view →
UCS	DFS	Median	IV	0.885	0.440	.015	30	view →
THCA	DFS	Median	All	0.769	0.894	.001	19	view →
READ	OS	Tertile	IV	0.948	0.467	.016	18	view →
PAAD	DFS	Tertile	All	0.207	0.437	.012	13	view →
BRCA	DFS	Tertile	All	0.647	0.456	.006	12	view →
DLBC	OS	Quartile	All	0.347	1.000	.022	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

DIAPH2-AS1–KIRC (OS)

Open the KIRC breakdown →