DIAPH1

Across TCGA patient cohorts, DIAPH1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,945 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DIAPH1-associated proteins across cancer lineages are G3BP1, HNRNPAB, and KDM3B. Each is linked with DIAPH1 in more than 4 cancer types. Because this analysis shows association rather than direction, both DIAPH1-to-partner and partner-to-DIAPH1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DIAPH1 versus G3BP1 in GBM, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DIAPH1→partner) and Y-score (partner→DIAPH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	G3BP1 →	+0.193	+0.321	<.001	<.001	3	5
LSCC	HNRNPAB →	+0.350	+0.533	<.001	<.001	3	5
LSCC	KDM3B →	+0.192	+0.441	.007	.001	3	5
GBM	NPM1 →	+0.369	+0.489	.001	<.001	3	5
GBM	DHFR →	+0.693	+0.424	<.001	.001	3	4
PDAC	EXOSC1 →	+0.436	+0.339	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,945 associations by consensus.

DIAPH1 vs G3BP1 — GBM

Explore this scatter interactively →