DHX40

Across TCGA patient cohorts, DHX40 protein abundance is significantly associated with the RNA expression of many other genes, with 12,228 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DHX40-associated genes across cancer lineages are RAD51C, RMND1, and SCML2. Each is linked with DHX40 in more than 4 cancer types. Because this analysis shows association rather than direction, both DHX40-to-partner and partner-to-DHX40 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DHX40 versus RAD51C in OV, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DHX40→partner) and Y-score (partner→DHX40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RAD51C →	+0.670	+0.344	<.001	.001	3	5
BRCA	RMND1 →	+0.838	+0.212	.001	.003	3	5
LSCC	SCML2 →	+1.049	+0.343	<.001	<.001	3	5
HNSC	NUP43 →	+0.502	+0.297	.005	.003	3	5
HNSC	UNK →	+0.679	+0.424	<.001	<.001	3	5
BRCA	MKS1 →	+0.552	+0.284	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,228 associations by consensus.

DHX40 vs RAD51C — OV

Explore this scatter interactively →