DHX32

Across TCGA patient cohorts, DHX32 mutation is significantly associated with the RNA expression of many other genes, with 3,021 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DHX32-associated genes across cancer lineages are LINC02353, SNORA74C-2, and STH. Each is linked with DHX32 in more than 1 cancer types. Because this analysis shows association rather than direction, both DHX32-to-partner and partner-to-DHX32 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02353 grouped by DHX32-low versus DHX32-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DHX32→partner) and Y-score (partner→DHX32) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	LINC02353 →	+0.042	+5.669	<.001	.003	3	2
READ	SNORA74C-2 →	+0.369	+5.039	<.001	.008	3	2
READ	STH →	+0.301	+5.219	<.001	.006	3	2
READ	ANKRD20A6P →	+0.261	+5.925	<.001	.002	3	2
READ	MIR6744 →	+1.700	+5.925	<.001	.002	3	2
BRCA	AP1B1P2 →	+0.281	+4.857	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,021 associations by consensus.

LINC02353 by DHX32 expression — CESC

Explore this box plot interactively →