DHX30

Across TCGA patient cohorts, DHX30 protein abundance is significantly associated with the protein abundance of many other proteins, with 30,176 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DHX30-associated proteins across cancer lineages are TOP2B, LRPPRC, and DCP1A. Each is linked with DHX30 in more than 8 cancer types. Because this analysis shows association rather than direction, both DHX30-to-partner and partner-to-DHX30 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DHX30 versus TOP2B in GBM, with a Pearson correlation of 0.68.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DHX30→partner) and Y-score (partner→DHX30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TOP2B →	+0.533	+0.289	<.001	<.001	3	9
LSCC	LRPPRC →	+0.580	+0.266	<.001	<.001	3	9
LSCC	DCP1A →	+0.250	+0.320	<.001	<.001	3	8
LSCC	DDX28 →	+0.515	+0.178	<.001	<.001	3	8
LSCC	CPSF2 →	+0.220	+0.307	<.001	<.001	3	8
LSCC	DDX23 →	+0.278	+0.234	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 30,176 associations by consensus.

DHX30 vs TOP2B — GBM

Explore this scatter interactively →