DHX30

Across TCGA cell cohorts, DHX30 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,476 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DHX30-associated GO terms across cancer lineages are Nucleosome disassembly, Regulation of double-strand break repair, and DNA-templated transcription elongation. Each is linked with DHX30 in more than 19 cancer types. Because this analysis shows association rather than direction, both DHX30-to-partner and partner-to-DHX30 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleosome disassembly grouped by DHX30-low versus DHX30-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DHX30→partner) and Y-score (partner→DHX30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Nucleosome disassembly →	+0.177	+0.774	<.001	<.001	3	20
BONE	Regulation of double-strand break repair →	+0.105	+0.813	<.001	<.001	3	19
OESOPHAGUS	DNA-templated transcription elongation →	+0.114	+0.956	.001	.002	3	19
STOMACH	Constitutive heterochromatin formation →	+0.098	+0.928	.006	<.001	3	18
BONE	Regulation of DNA recombination →	+0.085	+0.701	<.001	.002	3	18
LIVER	P-body assembly →	+0.120	+0.722	<.001	.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,476 associations by consensus.

Nucleosome disassembly by DHX30 expression — OVARY

Explore this box plot interactively →