DHX30

Across TCGA cell cohorts, DHX30 mutation is significantly associated with the RNA expression of many other genes, with 306 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DHX30-associated genes across cancer lineages are TAS2R39, OR8B4, and CLDN17. Each is linked with DHX30 in more than 2 cancer types. Because this analysis shows association rather than direction, both DHX30-to-partner and partner-to-DHX30 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAS2R39 grouped by DHX30-low versus DHX30-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DHX30→partner) and Y-score (partner→DHX30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	TAS2R39 →	+0.043	+4.906	<.001	.006	3	3
OESOPHAGUS	OR8B4 →	+0.036	+4.906	<.001	.006	3	1
LUNG_NSCLC_LUAD	CLDN17 →	+0.018	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR4F5 →	+0.012	+4.887	<.001	.009	3	1
OVARY	ASB17 →	+0.017	+4.807	<.001	.003	3	1
OVARY	HSF5 →	+0.006	+4.029	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 306 associations by consensus.

TAS2R39 by DHX30 expression — OESOPHAGUS

Explore this box plot interactively →