DHX15

Across TCGA cell cohorts, DHX15 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,586 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DHX15-associated GO terms across cancer lineages are Replication fork processing, DNA-templated DNA replication maintenance of fidelity, and DNA-templated DNA replication. Each is linked with DHX15 in more than 18 cancer types. Because this analysis shows association rather than direction, both DHX15-to-partner and partner-to-DHX15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Replication fork processing grouped by DHX15-low versus DHX15-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DHX15→partner) and Y-score (partner→DHX15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Replication fork processing →	+0.090	+0.807	<.001	<.001	3	19
BONE	DNA-templated DNA replication maintenance of fidelity →	+0.107	+0.583	.003	.006	3	19
BONE	DNA-templated DNA replication →	+0.145	+0.694	.006	.005	3	18
UPPER_AERODIGESTIVE_TRACT	DNA replication →	+0.094	+0.811	<.001	<.001	3	17
OVARY	Regulation of chromosome condensation →	+0.200	+0.660	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Mitotic G2/M transition checkpoint →	+0.072	+0.627	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,586 associations by consensus.

Replication fork processing by DHX15 expression — URINARY_TRACT

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