DHX15

Across TCGA pan-cancer cohorts, DHX15 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of DHX15’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where DHX15 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types DHX15 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

COAD, STAD, and LIHC are the cancer types where DHX15 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DHX15 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	II,III,IV	+0.596	<.001	10	view →
STAD	Male	II,III,IV	+0.997	<.001	9	view →
LIHC	All	II,III,IV	+0.985	<.001	9	view →
HNSC	All	III,IV	+0.667	<.001	9	view →
THCA	All	All	−0.399	<.001	8	view →
LUAD	Male	All	+0.579	<.001	6	view →
BRCA	All	II,III,IV	+0.442	<.001	6	view →
CHOL	Male	All	+2.308	<.001	5	view →
KICH	Female	All	−1.089	<.001	5	view →
BLCA	All	III,IV	+0.477	.001	5	view →
ESCA	All	All	+0.710	.009	4	view →
LUSC	All	All	+0.440	<.001	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

DHX15–COAD

Open the COAD breakdown →