Across TCGA patient cohorts, DHRSX-IT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,041 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DHRSX-IT1-associated GO terms across cancer lineages are Facultative heterochromatin formation, Sex-chromosome dosage compensation, and Obsolete histone methylation. Each is linked with DHRSX-IT1 in more than 25 cancer types. Because this analysis shows association rather than direction, both DHRSX-IT1-to-partner and partner-to-DHRSX-IT1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DHRSX-IT1→partner) and Y-score (partner→DHRSX-IT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	Facultative heterochromatin formation →	+0.047	+0.344	<.001	<.001	3	26
LAML	Sex-chromosome dosage compensation →	+0.053	+0.526	<.001	<.001	3	26
ESCA	Obsolete histone methylation →	+0.065	+0.435	.001	<.001	3	26
UVM	Protein sumoylation →	+0.050	+0.403	<.001	<.001	3	26
ESCA	Negative regulation of DNA biosynthetic process →	+0.044	+0.294	.005	.001	3	25
STAD	Centrosome duplication →	+0.059	+0.402	<.001	<.001	3	25

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,041 associations by consensus.

Exploration

DHRSX-IT1 survival (RNA) · tumor vs normal (RNA) · all DHRSX-IT1 data types