DHRSX-IT1

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, DHRSX-IT1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated DHRSX-IT1 data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher DHRSX-IT1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated DHRSX-IT1 expression acts as an unfavorable survival marker, although some lineages such as BLCA and OV show a favorable association.

BLCA, THCA, and OV are the cancer types where DHRSX-IT1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BLCAOSMedianIII,IV0.7110.431<.00150view →
THCADFSMedianII,III,IV0.7630.912.00147view →
OVDFSQuartileIII,IV0.4720.343.00436view →
LGGDFSMedianAll0.6680.807<.00135view →
MESODFSTertileIII,IV0.1130.637.01024view →
CESCDFSQuartileIII,IV0.4890.890.00224view →
LAMLDFSTertileAll0.6160.258.00124view →
KIRPDFSTertileAll0.5820.672.00223view →
CHOLOSMedianAll0.8470.570.01522view →
LUSCOSMedianII,III,IV0.7060.346.01213view →
SARCOSQuartileAll0.6550.860.0108view →
UVMOSQuartileAll0.7840.500.0306view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

Exploration