DHRS9

Across TCGA cell cohorts, DHRS9 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,080 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DHRS9-associated GO terms across cancer lineages are Cell-substrate junction assembly, Cell-substrate junction organization, and Regulation of actin filament polymerization. Each is linked with DHRS9 in more than 10 cancer types. Because this analysis shows association rather than direction, both DHRS9-to-partner and partner-to-DHRS9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cell-substrate junction assembly grouped by DHRS9-low versus DHRS9-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DHRS9→partner) and Y-score (partner→DHRS9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Cell-substrate junction assembly →	+0.202	+1.627	<.001	<.001	3	11
LUNG_NSCLC_LUAD	Cell-substrate junction organization →	+0.176	+1.608	<.001	<.001	3	11
PANCREAS	Regulation of actin filament polymerization →	+0.102	+3.763	<.001	<.001	3	10
LIVER	Regulation of cardiac muscle adaptation →	+0.331	+2.052	<.001	<.001	3	10
LIVER	Regulation of cardiac muscle hypertrophy in response to stress →	+0.331	+2.052	<.001	<.001	3	10
PANCREAS	Negative regulation of actin filament depolymerization →	+0.111	+3.276	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,080 associations by consensus.

Cell-substrate junction assembly by DHRS9 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →