DHRS9

Across TCGA cell cohorts, DHRS9 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DHRS9-associated genes across cancer lineages are FMO1, COX6A2, and BPIFB6. Each is linked with DHRS9 in more than 1 cancer types. Because this analysis shows association rather than direction, both DHRS9-to-partner and partner-to-DHRS9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FMO1 grouped by DHRS9-low versus DHRS9-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DHRS9→partner) and Y-score (partner→DHRS9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	FMO1 →	+0.131	+3.658	<.001	.005	3	1
LARGE_INTESTINE	COX6A2 →	+0.068	+4.022	<.001	.006	3	1
LARGE_INTESTINE	BPIFB6 →	+0.016	+4.022	<.001	.006	3	1
LARGE_INTESTINE	OR2AT4 →	+0.015	+3.196	.006	.007	3	1
LARGE_INTESTINE	KRTAP21-2 →	+0.057	+3.345	<.001	.007	3	1
LARGE_INTESTINE	NYX →	+0.046	+3.347	.004	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

FMO1 by DHRS9 expression — LARGE_INTESTINE

Explore this box plot interactively →