DHRS7B

Across TCGA pan-cancer cohorts, DHRS7B mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated DHRS7B data layer compared with 23 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher DHRS7B mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated DHRS7B expression acts as an unfavorable survival marker, although some lineages such as COAD and LUAD show a favorable association.

COAD, HNSC, and OV are the cancer types where DHRS7B mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	All	1.000	0.871	.045	18	view →
HNSC	DFS	Tertile	III,IV	0.516	0.840	.006	12	view →
OV	DFS	Median	All	0.637	0.907	.025	4	view →
LUAD	OS	Median	III,IV	0.689	0.210	.006	2	view →
PDAC	DFS	Median	III,IV	0.533	0.224	.031	2	view →
LSCC	OS	Quartile	All	1.000	0.681	.042	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

DHRS7B–COAD (DFS)

Open the COAD breakdown →