DHRS7B

Across TCGA patient cohorts, DHRS7B mutation is significantly associated with the total protein of many other genes, with 22 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DHRS7B-associated genes across cancer lineages are eIF4G, Fibronectin, and Acetyl-a-Tubulin-Lys40. Each is linked with DHRS7B in more than 1 cancer types. Because this analysis shows association rather than direction, both DHRS7B-to-partner and partner-to-DHRS7B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eIF4G grouped by DHRS7B-low versus DHRS7B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DHRS7B→partner) and Y-score (partner→DHRS7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4G →	+0.272	+3.169	.025	.018	3	1
UCEC	Fibronectin →	-0.263	-2.105	.042	.017	3	1
UCEC	Acetyl-a-Tubulin-Lys40 →	+0.416	+1.584	.037	.036	3	1
UCEC	HSP70 →	-0.352	-2.312	.025	.034	3	1
UCEC	INPP4B →	-0.355	-3.700	.005	.001	3	1
UCEC	JNK2 →	+0.204	+1.584	.009	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

eIF4G by DHRS7B expression — UCEC

Explore this box plot interactively →