Across TCGA pan-cancer cohorts, DHRS4L1 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated DHRS4L1 data layer compared with 23 for mass-spec protein.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher DHRS4L1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated DHRS4L1 expression acts as an unfavorable survival marker.

STAD and COAD are the cancer types where DHRS4L1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Median	All	0.234	0.689	.003	24	view →
COAD	DFS	Median	All	0.170	0.790	.002	15	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: DHRS4L1 tumor-vs-normal RNA expression · all DHRS4L1 data types