Across TCGA patient cohorts, DHRS4L1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,622 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DHRS4L1-associated proteins across cancer lineages are SMC3, SSRP1, and PLAU. Each is linked with DHRS4L1 in more than 5 cancer types. Because this analysis shows association rather than direction, both DHRS4L1-to-partner and partner-to-DHRS4L1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DHRS4L1→partner) and Y-score (partner→DHRS4L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SMC3 →	+0.218	+0.404	<.001	<.001	3	6
LSCC	SSRP1 →	+0.399	+0.484	<.001	<.001	3	6
CCRCC	PLAU →	-0.807	-0.494	.003	.009	3	5
LSCC	KDM1A →	+0.350	+0.550	<.001	<.001	3	5
LSCC	ATG7 →	-0.205	-0.462	<.001	<.001	3	5
GBM	SMC1A →	+0.234	+0.291	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,622 associations by consensus.

Exploration

DHRS4L1 survival (RNA) · tumor vs normal (RNA) · all DHRS4L1 data types