DHRS4

Across TCGA patient cohorts, DHRS4 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,410 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DHRS4-associated proteins across cancer lineages are SSRP1, PRMT5, and MTHFD1. Each is linked with DHRS4 in more than 6 cancer types. Because this analysis shows association rather than direction, both DHRS4-to-partner and partner-to-DHRS4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DHRS4 versus SSRP1 in OV, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DHRS4→partner) and Y-score (partner→DHRS4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SSRP1 →	+0.384	+0.457	<.001	<.001	3	7
COAD	PRMT5 →	+0.270	+0.771	<.001	<.001	3	6
OV	MTHFD1 →	+0.446	+0.469	<.001	.002	3	6
OV	SUPT16H →	+0.329	+0.368	<.001	<.001	3	6
OV	FKBP3 →	+0.413	+0.675	<.001	<.001	3	6
CCRCC	RRBP1 →	-0.414	-0.661	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,410 associations by consensus.

DHRS4 vs SSRP1 — OV

Explore this scatter interactively →