DHRS4-AS1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DHRS4-AS1 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DHRS4-AS1-associated genes across cancer lineages are OR6C70, RFKP1, and RPL35AP12. Each is linked with DHRS4-AS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DHRS4-AS1-to-partner and partner-to-DHRS4-AS1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DHRS4-AS1→partner) and Y-score (partner→DHRS4-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECOR6C70 →+0.075+5.551.008.00431
UCECRFKP1 →+0.226+5.242.001.00731
UCECRPL35AP12 →+0.233+5.937.001.00231
UCECRNU7-29P →+0.778+6.722<.001<.00131
UCECIGLVI-68 →+0.286+5.852<.001.00331
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

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