DHRS2

Across TCGA cell cohorts, DHRS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,179 significant associations in total. URINARY_TRACT shows the largest number of these associations.

The most reproducible DHRS2-associated GO terms across cancer lineages are Myeloid dendritic cell differentiation, Nucleoside phosphate biosynthetic process, and Regulation of acrosome reaction. Each is linked with DHRS2 in more than 8 cancer types. Because this analysis shows association rather than direction, both DHRS2-to-partner and partner-to-DHRS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Myeloid dendritic cell differentiation grouped by DHRS2-low versus DHRS2-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DHRS2→partner) and Y-score (partner→DHRS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Myeloid dendritic cell differentiation →	+0.887	+4.205	.001	<.001	3	9
OESOPHAGUS	Nucleoside phosphate biosynthetic process →	+0.043	+2.523	.002	.008	3	9
LIVER	Regulation of acrosome reaction →	-1.608	-1.852	<.001	.001	3	7
PANCREAS	Regulation of ubiquitin-dependent protein catabolic process →	+0.032	+1.044	.005	.006	3	7
PANCREAS	Negative regulation of ubiquitin-dependent protein catabolic process →	+0.054	+1.362	.005	.008	3	6
BLOOD_Lymphoma	Vacuole organization →	+0.028	+2.033	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,179 associations by consensus.

Myeloid dendritic cell differentiation by DHRS2 expression — URINARY_TRACT

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