DHRS13

Across TCGA pan-cancer cohorts, DHRS13 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated DHRS13 data layer compared with 20 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher DHRS13 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated DHRS13 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

GBM, CCRCC, and HNSC are the cancer types where DHRS13 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	DFS	Quartile	All	0.249	0.489	.006	15	view →
CCRCC	DFS	Median	III,IV	1.000	0.821	.024	13	view →
HNSC	DFS	Median	II,III,IV	0.894	0.978	.033	5	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

DHRS13–GBM (DFS)

Open the GBM breakdown →