DHRS13

Across TCGA pan-cancer cohorts, DHRS13 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of DHRS13’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where DHRS13 RNA is repressed in tumor relative to normal tissue. In most cancer types DHRS13 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

KICH, LIHC, and BLCA are the cancer types where DHRS13 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DHRS13 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	II,III,IV	−1.504	<.001	11	view →
LIHC	Male	All	+0.876	<.001	9	view →
BLCA	All	III,IV	+1.317	<.001	8	view →
BRCA	All	III,IV	+0.977	<.001	8	view →
LUAD	Female	All	+0.814	<.001	8	view →
COAD	Female	II,III,IV	+0.781	<.001	8	view →
LUSC	Female	All	+1.490	<.001	7	view →
HNSC	Male	All	+0.742	<.001	7	view →
UCEC	All	III,IV	+1.384	.002	6	view →
STAD	Male	All	+0.831	<.001	4	view →
THCA	Male	All	−0.360	.002	4	view →
CHOL	All	All	+1.476	<.001	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

DHRS13–KICH

Open the KICH breakdown →