DHRS13

Across TCGA cell cohorts, DHRS13 mutation is significantly associated with the RNA expression of many other genes, with 22 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DHRS13-associated genes across cancer lineages are PACRG, C6orf118, and BTBD16. Each is linked with DHRS13 in more than 1 cancer types. Because this analysis shows association rather than direction, both DHRS13-to-partner and partner-to-DHRS13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PACRG grouped by DHRS13-low versus DHRS13-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DHRS13→partner) and Y-score (partner→DHRS13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	PACRG →	+0.209	+3.769	.003	.004	3	1
BLOOD_Leukemia	C6orf118 →	+0.051	+3.450	<.001	.004	3	1
BLOOD_Leukemia	BTBD16 →	+0.085	+4.281	<.001	.001	3	1
BLOOD_Leukemia	OR9G1 →	+0.215	+3.289	<.001	.009	3	1
BLOOD_Leukemia	SIX6 →	+1.040	+4.091	.005	.002	3	1
BLOOD_Leukemia	PRR30 →	+0.015	+3.684	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

PACRG by DHRS13 expression — BLOOD_Leukemia

Explore this box plot interactively →