DHRS1

Across TCGA cell cohorts, DHRS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,371 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible DHRS1-associated GO terms across cancer lineages are Negative regulation of supramolecular fiber organization, Positive regulation of translational elongation, and Negative regulation of actin filament polymerization. Each is linked with DHRS1 in more than 9 cancer types. Because this analysis shows association rather than direction, both DHRS1-to-partner and partner-to-DHRS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of supramolecular fiber organization grouped by DHRS1-low versus DHRS1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DHRS1→partner) and Y-score (partner→DHRS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of supramolecular fiber organization →	+0.092	+1.229	<.001	<.001	3	10
KIDNEY	Positive regulation of translational elongation →	-0.064	-0.735	.002	.001	2	10
STOMACH	Negative regulation of actin filament polymerization →	+0.125	+0.893	<.001	.002	3	9
STOMACH	Negative regulation of protein polymerization →	+0.125	+0.864	<.001	.002	3	9
LARGE_INTESTINE	Positive regulation of GTPase activity →	+0.048	+0.628	.001	.001	3	9
PANCREAS	Negative regulation of tumor necrosis factor production →	+0.094	+0.970	.005	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,371 associations by consensus.

Negative regulation of supramolecular fiber organization by DHRS1 expression — STOMACH

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