DHPS

Across TCGA patient cohorts, DHPS RNA expression is significantly associated with the protein abundance of many other proteins, with 16,663 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DHPS-associated proteins across cancer lineages are XAB2, SIN3A, and HCFC1. Each is linked with DHPS in more than 6 cancer types. Because this analysis shows association rather than direction, both DHPS-to-partner and partner-to-DHPS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DHPS versus XAB2 in GBM, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DHPS→partner) and Y-score (partner→DHPS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	XAB2 →	+0.283	+0.466	<.001	<.001	3	7
HNSC	SIN3A →	+0.258	+0.602	<.001	<.001	3	6
GBM	HCFC1 →	+0.228	+0.467	<.001	<.001	3	6
HNSC	HNRNPA3 →	+0.263	+0.492	.001	<.001	3	6
GBM	HNRNPR →	+0.332	+0.460	<.001	<.001	3	6
HNSC	HNRNPU →	+0.239	+0.441	<.001	.006	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,663 associations by consensus.

DHPS vs XAB2 — GBM

Explore this scatter interactively →