DHCR7

Across TCGA patient cohorts, DHCR7 protein abundance is significantly associated with the protein abundance of many other proteins, with 17,446 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DHCR7-associated proteins across cancer lineages are CCDC47, UBAC2, and EMC1. Each is linked with DHCR7 in more than 8 cancer types. Because this analysis shows association rather than direction, both DHCR7-to-partner and partner-to-DHCR7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DHCR7 versus CCDC47 in UCEC, with a Pearson correlation of 0.67.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DHCR7→partner) and Y-score (partner→DHCR7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CCDC47 →	+0.435	+1.110	<.001	<.001	3	9
BRCA	UBAC2 →	+0.458	+0.843	<.001	<.001	3	9
UCEC	EMC1 →	+0.421	+1.013	<.001	<.001	3	9
PDAC	CLPTM1 →	+0.678	+0.816	<.001	<.001	3	8
UCEC	RPN1 →	+0.636	+1.054	<.001	<.001	3	8
BRCA	TMX2 →	+0.722	+1.016	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,446 associations by consensus.

DHCR7 vs CCDC47 — UCEC

Explore this scatter interactively →