DGUOK-AS1

Across TCGA pan-cancer cohorts, DGUOK-AS1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated DGUOK-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher DGUOK-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated DGUOK-AS1 expression acts as an unfavorable survival marker, although some lineages such as LUSC and THCA show a favorable association.

KIRC, ACC, and LIHC are the cancer types where DGUOK-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.546	0.704	<.001	151	view →
ACC	DFS	Median	All	0.297	0.599	<.001	123	view →
LIHC	OS	Quartile	All	0.397	0.745	<.001	57	view →
BRCA	DFS	Quartile	II,III,IV	0.848	0.931	.003	40	view →
COAD	DFS	Quartile	All	0.390	0.635	.004	39	view →
LGG	DFS	Median	All	0.662	0.809	<.001	38	view →
KIRP	OS	Quartile	II,III,IV	0.197	0.879	.010	32	view →
KICH	DFS	Tertile	II,III,IV	0.742	1.000	.024	23	view →
UVM	DFS	Quartile	III,IV	0.170	0.813	.003	20	view →
LUSC	DFS	Median	II,III,IV	0.486	0.321	.009	16	view →
DLBC	DFS	Median	All	0.147	0.929	.001	15	view →
THCA	OS	Median	III,IV	1.000	0.329	.006	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

DGUOK-AS1–KIRC (OS)

Open the KIRC breakdown →