DGUOK-AS1

Across TCGA pan-cancer cohorts, DGUOK-AS1 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of DGUOK-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where DGUOK-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types DGUOK-AS1 is over-expressed in tumor, although a few such as KICH and KIRC show the opposite, repressed pattern.

LIHC, LUSC, and BLCA are the cancer types where DGUOK-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DGUOK-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	All	II,III,IV	+0.526	<.001	8	view →
LUSC	Female	All	+1.516	<.001	7	view →
BLCA	All	All	+1.142	.005	7	view →
HNSC	Male	IV	+1.235	.003	6	view →
THCA	Female	II,III,IV	+1.154	<.001	6	view →
KICH	All	All	−0.746	<.001	6	view →
BRCA	All	II,III,IV	+0.601	<.001	6	view →
CHOL	Male	All	+2.146	<.001	5	view →
UCEC	All	All	+0.984	<.001	2	view →
KIRC	Male	All	−0.190	.022	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

DGUOK-AS1–LIHC

Open the LIHC breakdown →