DGLUCY

Across TCGA patient cohorts, DGLUCY protein abundance is significantly associated with the RNA expression of many other genes, with 5,116 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DGLUCY-associated genes across cancer lineages are CHEK2, GARS1, and CEP55. Each is linked with DGLUCY in more than 3 cancer types. Because this analysis shows association rather than direction, both DGLUCY-to-partner and partner-to-DGLUCY results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DGLUCY versus CHEK2 in BRCA, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DGLUCY→partner) and Y-score (partner→DGLUCY) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CHEK2 →	-0.742	-0.801	<.001	<.001	3	4
OV	GARS1 →	-0.409	-0.669	.008	.005	3	3
BRCA	CEP55 →	-1.139	-0.544	<.001	<.001	3	3
BRCA	CHEK1 →	-0.765	-0.495	<.001	.002	3	3
OV	DEPDC1 →	-0.715	-0.499	<.001	.009	3	3
HNSC	NR3C2 →	+1.089	+0.640	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,116 associations by consensus.

DGLUCY vs CHEK2 — BRCA

Explore this scatter interactively →