DGLUCY

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, DGLUCY RNA expression is significantly associated with the go_rna of many other GO terms, with 3,271 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DGLUCY-associated GO terms across cancer lineages are Regulation of telomere maintenance, Modulation of process of another organism, and Glutamate metabolic process. Each is linked with DGLUCY in more than 9 cancer types. Because this analysis shows association rather than direction, both DGLUCY-to-partner and partner-to-DGLUCY results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of telomere maintenance grouped by DGLUCY-low versus DGLUCY-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DGLUCY→partner) and Y-score (partner→DGLUCY) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PANCREASRegulation of telomere maintenance →+0.058+1.157<.001.004310
KIDNEYModulation of process of another organism →+0.097+1.801<.001<.001310
UPPER_AERODIGESTIVE_TRACTGlutamate metabolic process →+0.114+1.580.001<.00139
URINARY_TRACTIntrinsic apoptotic signaling pathway by p53 class mediator →+0.084+2.410.002.00339
LARGE_INTESTINERegulation of intracellular steroid hormone receptor signaling pathway →+0.055+1.013.001.00938
KIDNEYHost-mediated perturbation of viral process →+0.071+1.394<.001<.00129
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,271 associations by consensus.

Regulation of telomere maintenance by DGLUCY expression — PANCREAS

Box plot of Regulation of telomere maintenance in DGLUCY-low vs DGLUCY-high samples in PANCREAS.

Explore this box plot interactively →

Exploration