DGKQ

Across TCGA pan-cancer cohorts, DGKQ mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated DGKQ data layer compared with 22 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher DGKQ mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated DGKQ expression acts as an unfavorable survival marker, although some lineages such as CCRCC and PDAC show a favorable association.

CCRCC, PDAC, and LSCC are the cancer types where DGKQ mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Quartile	II,III,IV	1.000	0.476	.001	42	view →
PDAC	OS	Quartile	All	0.981	0.694	.003	38	view →
LSCC	DFS	Tertile	III,IV	0.510	1.000	.007	8	view →
LUAD	OS	Median	II,III,IV	0.732	0.441	.027	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

DGKQ–CCRCC (OS)

Open the CCRCC breakdown →