DGKK

Across TCGA patient cohorts, DGKK protein abundance is significantly associated with the protein abundance of many other proteins, with 104 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DGKK-associated proteins across cancer lineages are SESN1, SPECC1_S553, and EPG5. Each is linked with DGKK in more than 1 cancer types. Because this analysis shows association rather than direction, both DGKK-to-partner and partner-to-DGKK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DGKK versus SESN1 in GBM, with a Pearson correlation of 0.76.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DGKK→partner) and Y-score (partner→DGKK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SESN1 →	+0.483	+1.344	<.001	<.001	3	1
GBM	SPECC1_S553 →	-0.926	-1.532	.001	.003	3	1
GBM	EPG5 →	-0.326	-1.632	<.001	.001	3	1
GBM	MAST4_S2442 →	+1.048	+1.853	<.001	.002	3	1
GBM	NAV3_S1186 →	+1.202	+1.906	.004	.001	3	1
GBM	NHSL1_S723 →	+0.514	+1.217	.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 104 associations by consensus.

DGKK vs SESN1 — GBM

Explore this scatter interactively →