DGKK

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, DGKK RNA expression is significantly associated with the go_rna of many other GO terms, with 476 significant associations in total. LIVER shows the largest number of these associations.

The most reproducible DGKK-associated GO terms across cancer lineages are Plasma lipoprotein particle assembly, Regulation of plasma lipoprotein particle levels, and Plasma lipoprotein particle clearance. Each is linked with DGKK in more than 3 cancer types. Because this analysis shows association rather than direction, both DGKK-to-partner and partner-to-DGKK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Plasma lipoprotein particle assembly grouped by DGKK-low versus DGKK-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DGKK→partner) and Y-score (partner→DGKK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LIVERPlasma lipoprotein particle assembly →+0.234+3.077<.001<.00134
LIVERRegulation of plasma lipoprotein particle levels →+0.151+1.681.002.00434
LIVERPlasma lipoprotein particle clearance →+0.205+2.473.004.00233
LIVERProtein-lipid complex assembly →+0.188+2.717.001.00633
BLOOD_LeukemiaPositive regulation of intrinsic apoptotic signaling pathway by p53 class mediator →+0.068+0.008<.001.00432
BLOOD_LeukemiaCellular component disassembly →+0.022+0.007.002.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 476 associations by consensus.

Plasma lipoprotein particle assembly by DGKK expression — LIVER

Box plot of Plasma lipoprotein particle assembly in DGKK-low vs DGKK-high samples in LIVER.

Explore this box plot interactively →

Exploration