DGKI

Across TCGA patient cohorts, DGKI protein abundance is significantly associated with the RNA expression of many other genes, with 3,535 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DGKI-associated genes across cancer lineages are RNU1-51P, IFITM3P7, and PDZRN3-AS1. Each is linked with DGKI in more than 1 cancer types. Because this analysis shows association rather than direction, both DGKI-to-partner and partner-to-DGKI results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DGKI versus RNU1-51P in BRCA, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DGKI→partner) and Y-score (partner→DGKI) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNU1-51P →	+0.858	+1.542	.005	.001	3	1
BRCA	IFITM3P7 →	+0.335	+0.964	.006	.003	3	1
BRCA	PDZRN3-AS1 →	+0.139	+1.164	.009	.004	3	1
BRCA	OR52H2P →	+0.186	+1.557	.003	.002	3	1
BRCA	BCS1L →	-0.511	-0.473	.004	.007	3	1
GBM	UPB1 →	+0.214	+0.384	.002	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,535 associations by consensus.

DGKI vs RNU1-51P — BRCA

Explore this scatter interactively →