DGKG

Across TCGA patient cohorts, DGKG RNA expression is significantly associated with the protein abundance of many other proteins, with 12,432 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible DGKG-associated proteins across cancer lineages are UCHL1, MAP1B_S614, and WIPF3. Each is linked with DGKG in more than 4 cancer types. Because this analysis shows association rather than direction, both DGKG-to-partner and partner-to-DGKG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DGKG versus UCHL1 in HNSC, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DGKG→partner) and Y-score (partner→DGKG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	UCHL1 →	+1.339	+0.812	<.001	.002	3	5
LSCC	MAP1B_S614 →	+1.340	+1.035	<.001	<.001	3	5
CCRCC	WIPF3 →	+0.907	+0.763	<.001	<.001	3	4
LSCC	TXNRD1 →	+0.643	+1.257	<.001	<.001	3	4
HNSC	PPP1R13L →	-0.457	-0.693	<.001	<.001	3	4
HNSC	RAB6B →	+0.975	+1.036	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,432 associations by consensus.

DGKG vs UCHL1 — HNSC

Explore this scatter interactively →