DGKE

Across TCGA patient cohorts, DGKE RNA expression is significantly associated with the protein abundance of many other proteins, with 22,020 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DGKE-associated proteins across cancer lineages are SMC1A, GIT1, and SIN3A. Each is linked with DGKE in more than 4 cancer types. Because this analysis shows association rather than direction, both DGKE-to-partner and partner-to-DGKE results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DGKE versus SMC1A in LSCC, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DGKE→partner) and Y-score (partner→DGKE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SMC1A →	+0.239	+0.693	<.001	<.001	3	5
GBM	GIT1 →	+0.218	+0.579	<.001	<.001	3	5
LSCC	SIN3A →	+0.264	+0.666	<.001	<.001	3	4
LSCC	SMARCA2_S329 →	+0.619	+0.449	<.001	<.001	3	4
LSCC	SMARCB1 →	+0.175	+0.456	<.001	<.001	3	4
PDAC	SMARCC2_S347 →	+0.524	+0.200	.008	.004	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,020 associations by consensus.

DGKE vs SMC1A — LSCC

Explore this scatter interactively →