DGKD

Across TCGA patient cohorts, DGKD RNA expression is significantly associated with the RNA expression of many other genes, with 21,101 significant associations in total. ACC shows the largest number of these associations.

The most reproducible DGKD-associated genes across cancer lineages are SMG1, GARRE1, and RALGAPB. Each is linked with DGKD in more than 33 cancer types. Because this analysis shows association rather than direction, both DGKD-to-partner and partner-to-DGKD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DGKD versus SMG1 in UVM, with a Pearson correlation of 0.56.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DGKD→partner) and Y-score (partner→DGKD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	SMG1 →	+1.475	+0.922	<.001	<.001	3	34
KICH	GARRE1 →	+1.031	+0.741	<.001	.002	3	34
KICH	RALGAPB →	+0.863	+0.723	.001	.003	3	34
SCLC	CHD2 →	+1.127	+1.382	<.001	.002	3	34
SCLC	MDC1 →	+1.437	+2.136	<.001	<.001	3	34
SCLC	KMT2B →	+1.320	+1.787	<.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,101 associations by consensus.

DGKD vs SMG1 — UVM

Explore this scatter interactively →