DGKD

Across TCGA cell cohorts, DGKD RNA expression is significantly associated with the go_rna of many other GO terms, with 5,054 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DGKD-associated GO terms across cancer lineages are Positive regulation of clathrin-dependent endocytosis, Negative regulation of phospholipase C/protein kinase C signal transduction, and Cytosolic transport. Each is linked with DGKD in more than 17 cancer types. Because this analysis shows association rather than direction, both DGKD-to-partner and partner-to-DGKD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of clathrin-dependent endocytosis grouped by DGKD-low versus DGKD-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DGKD→partner) and Y-score (partner→DGKD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Positive regulation of clathrin-dependent endocytosis →	+0.231	+1.573	<.001	<.001	3	18
PANCREAS	Negative regulation of phospholipase C/protein kinase C signal transduction →	+0.857	+1.396	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Cytosolic transport →	+0.079	+0.917	<.001	.005	2	13
BREAST	Regulation of cilium assembly →	+0.063	+1.095	<.001	<.001	3	12
BONE	Pre-mRNA catabolic process →	+0.206	+1.843	<.001	<.001	3	12
SKIN	Regulation of centriole-centriole cohesion →	+0.147	+1.352	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,054 associations by consensus.

Positive regulation of clathrin-dependent endocytosis by DGKD expression — BLOOD_Lymphoma

Explore this box plot interactively →