DGKB

Across TCGA patient cohorts, DGKB RNA expression is significantly associated with the RNA expression of many other genes, with 15,606 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible DGKB-associated genes across cancer lineages are CSRNP3, LCA5, and ZEB1. Each is linked with DGKB in more than 21 cancer types. Because this analysis shows association rather than direction, both DGKB-to-partner and partner-to-DGKB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DGKB versus CSRNP3 in TGCT, with a Pearson correlation of 0.85.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DGKB→partner) and Y-score (partner→DGKB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	CSRNP3 →	+0.946	+0.371	<.001	<.001	3	22
KIRP	LCA5 →	+0.858	+0.122	<.001	<.001	3	22
UCS	ZEB1 →	+1.585	+0.658	<.001	.001	3	21
SKCM	ZDHHC17 →	+0.958	+0.216	<.001	<.001	3	21
SKCM	FAM172A →	+1.115	+0.196	<.001	<.001	3	21
SKCM	DHX36 →	+0.705	+0.133	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,606 associations by consensus.

DGKB vs CSRNP3 — TGCT

Explore this scatter interactively →