DGKB

Across TCGA patient cohorts, DGKB RNA expression is significantly associated with the protein abundance of many other proteins, with 16,261 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DGKB-associated proteins across cancer lineages are CRMP1, PURA, and CAVIN1. Each is linked with DGKB in more than 5 cancer types. Because this analysis shows association rather than direction, both DGKB-to-partner and partner-to-DGKB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DGKB versus CRMP1 in LSCC, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DGKB→partner) and Y-score (partner→DGKB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CRMP1 →	+0.816	+0.422	<.001	.002	3	6
UCEC	PURA →	+0.353	+0.783	<.001	<.001	3	6
UCEC	CAVIN1 →	+1.013	+0.699	<.001	<.001	3	5
CCRCC	PTPN1 →	-0.410	-0.464	<.001	.001	3	5
UCEC	SEPTIN7 →	+0.309	+0.734	<.001	<.001	3	5
UCEC	TNS2_S120 →	+0.666	+0.678	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,261 associations by consensus.

DGKB vs CRMP1 — LSCC

Explore this scatter interactively →